Research of the New Biomarkers of Mammary Gland Tumors in Domestic Cats

This article presents the results of clinical significance study changes in activity adenosine deaminase and content polyamines blood plasma cats with mammary gland tumors. In our work, we investigated gene tissues tumors compared this normal tissue. course also found out frequency occurrence population domestic Rostov region evaluated prognosis survival after surgical treatment breast cancer. The incidence was detected, which amounted to 0.4% who have applied veterinary clinics region, where neoplasms approximately 400 individuals for every 100,000 animals. These data reflect importance problem emphasize need pathophysiological foundations carcinogenesis order create molecular genetic approaches early diagnosis studies showed that level expression invasive nonspecific carcinoma fibroepithelial hyperplasia sharply increases tissue a healthy gland, 36 times carcinomas 131 hyperplasia. At same time, there were no significant differences between animals malignant gland. Measurement putrescine erythrocytes benign tumor-like significantly increased by 5 indicators control group. carcinoma, spermin exceeded values 6 10 times, respectively.